NASA SBIR 2010 Solicitation

FORM B - PROPOSAL SUMMARY


PROPOSAL NUMBER: 10-1 X16.01-9831
SUBTOPIC TITLE: Alternative Methods for Ambient Preservation of Human Biological Samples During Extended Spaceflight and Planetary Operations
PROPOSAL TITLE: Ambient Preservation of Clinical Analytes

SMALL BUSINESS CONCERN (Firm Name, Mail Address, City/State/Zip, Phone)
Connecticut Analytical Corporation
696 Amity Road
Bethany, CT 06524 - 3006
(203) 393-9666

PRINCIPAL INVESTIGATOR/PROJECT MANAGER (Name, E-mail, Mail Address, City/State/Zip, Phone)
Joseph J Bango
jbango@ctanalytical.com
696 Amity Road
Bethany, CT 06524 - 3006
(203) 393-9666 Extension :21

Estimated Technology Readiness Level (TRL) at beginning and end of contract:
Begin: 3
End: 4

TECHNICAL ABSTRACT (Limit 2000 characters, approximately 200 words)
The proposed research is in response to the In-flight Biological Sample Preservation and Analysis topic and offers a non-invasive, proven, space and cost and time effective approach to biological sample collection and preservation. Our proposal is to collect capillary whole blood from the fingertip in addition to urine samples, and to store these samples as dried spots on a custom wick-matrix. The process of sample collection is minimally invasive to non-invasive, and samples can be stored efficiently at ambient temperatures during space flight. A wide array of blood analytes can already be determined from these samples, but in addition, we propose to develop and validate further assays that meet the specific objectives of NASA, its scientists and clinicians.

POTENTIAL NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
Some of the many NASA applications include the potential to monitor crew health on long duration space missions with an on-board analyzer, or to predict emerging crew health concerns through known biomarker identification. In addition, health histories of previous astronauts can be catalogued using actual dried biological samples, which can be referenced, and analyzed at a later date should a health issue later transpire.

POTENTIAL NON-NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
The market potential for simple and reliable and low cost analyte capture and analysis for the diagnosis and prognosis of disease and overall physiological health are enormous. The potential exists for a markedly increasing advanced medical diagnostic testing in the developing world and rural regions worldwide. The resulting cost savings to healthcare can run into the hundreds of millions of dollars, and offer a venue by which home health care can become more prevalent.

TECHNOLOGY TAXONOMY MAPPING (NASA's technology taxonomy has been developed by the SBIR-STTR program to disseminate awareness of proposed and awarded R/R&D in the agency. It is a listing of over 100 technologies, sorted into broad categories, of interest to NASA.)
Analytical Methods
Health Monitoring & Sensing (see also Sensors)
Medical


Form Generated on 09-03-10 12:12